Recurrent fibrosarcoma of maxillary sinus involving the cranial base: A rare case
Lei Jin, Hong-Yu Yang, Yu-Fan Wang, Hui-Jun YangJournal of Cancer Research and Therapeutics 2018 14(9):542-543Adult fibrosarcoma (FS) of the maxillary sinus and the cranial base is a rare soft tissue sarcoma which is clinically characterized by a high frequency of local repeated recurrence if not excised widely. At present, the standard treatment option for FS is surgical resection. Here, we report a case of a 46-year-old male with a 5 months history recurrent FS of the maxillary sinus. The patient possessed an enormous mass in the right maxillofacial region extending to the cranial base, as observed by computed tomography. Histologically, the lessions were composed of hypercellular cells with heterogenous groups. The recurrence and pathologically heterogenous groups of FS lead to therapeutic complexities. Due to the challenging anatomy in head and neck region, it is crucial to define the lesion areas and weigh the balance between life quality and functional reconstruction.
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In this study, 1452 patients were enrolled. Independent risk factors for recurrence-free survival (RFS) and overall survival (OS) were analyzed for patients with and without CSPH. For HCC patients without CSPH, multivariate analysis suggested that microvascular invasion (MVI), neutrophil-to-lymphocyte ratio (NLR) ≥ 3, platelet-to-lymphocyte ratio (PLR) ≥ 150, tumor size> 5 cm, and the presence of a satellite lesion were independently associated with RFS. MVI, NLR ≥ 3, PLR ≥ 150, and advanced Barcelona clinical liver cancer (BCLC) stage contributed to mortality. However, neither NLR nor PLR showed any prognos...
LUNG cancer symptoms include difficulty breathing, headaches, and persistent chest pain. But you could also be at risk of a tumour if you notice a subtle change to your voice. This is the warning sign of lung cancer you should be looking out for when you speak.
Publication date: Available online 10 July 2020Source: Cancer EpidemiologyAuthor(s): K. Waddell, M. Matua, C. Bidwell, R. Atwine, J. Onyango, S.V. Picton, I. Simmons, J. Stahlschmidt, W.T. Johnston, R. Newton
Conclusion: HRR is a new prognostic factor that can be used to predict PFS/OS in MIBC. PMID: 32648774 [PubMed - as supplied by publisher]