Low plasma concentrations of N-methyl-d-aspartate receptor subunits as a possible biomarker for psychosis

N-methyl-d-aspartate receptor (NMDAR) has been largely implicated in the neurobiology of schizophrenia and other psychosis. Aiming to evaluate their potential as peripheral biomarkers for psychosis, we quantified the plasma concentrations of NR1 and NR2 NMDAR subunits of first-episode psychosis patients in their first contact with mental health services due to psychotic symptoms, compared with siblings and matched community-based controls.

Source: Schizophrenia Research - June 21, 2018 Category: Psychiatry Authors: C.M. Loureiro, R. Shuhama, H.A. Fachim, P.R. Menezes, C.M. Del-Ben, P. Louzada-Junior Source Type: research