Secretory Clusterin Mediates Oxaliplatin Resistance via the Gadd45a/PI3K/Akt Signaling Pathway in Hepatocellular Carcinoma

Conclusions: The results demonstrate that sCLU/Gadd45a/PI3K/Akt signaling represents a novel pathway that could regulate drug resistance in a one-way manner in HCC cells.

Source: Journal of Cancer - June 20, 2018 Category: Cancer & Oncology Authors: Xin Wang, Fang Zou, Jingtao Zhong, Longtao Yue, Fuhai Wang, Honglong Wei, Guangsheng Yang, Tao Jin, Xiaofeng Dong, Jie Li, Peng Xiu Tags: Research Paper Source Type: research