Autophagy activation in circulating proangiogenic cells (PACs) aggravates AKI in type I diabetes mellitus.

CONCLUSION: Pharmacological autophagy activation may most likely not serve as effective strategy for improving PAC competence in diabetic AKI in general. On the contrary, several outcome parameters (excretory function, fibrosis, EndoMT) may even be worsened. PMID: 29897281 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29897281?dopt=Abstract

Source: Am J Physiol Renal P... - June 13, 2018 Category: Urology & Nephrology Authors: Schwarze K, Kribben A, Ritter O, Müller GA, Patschan D Tags: Am J Physiol Renal Physiol Source Type: research