Hemodynamic effects of short-term infusion of a vasopressin V1A/V2 receptor antagonist conivaptan in patients with chronic heart failure during submaximal exercise

Publication date: Available online 14 June 2018 Source:American Heart Journal Author(s): L Balling, J.H Thomsen, E Wolsk, C Hassager, S Boesgaard, S Goldsmith, F Gustafsson Heart failure (HF) is associated with a reduced exercise capacity. Our aim was to investigate if infusion with a V1A/V2-receptor antagonist, conivaptan, leads to an increase in cardiac output (CO) at a constant or reduced filling pressure (PCWP) during submaximal exercise.
Source: American Heart Journal - Category: Cardiology Source Type: research