C –N Cross-Coupling via Photoexcitation of Nickel–Amine Complexes

JacsC –N Cross-Coupling via Photoexcitation of Nickel–Amine ComplexesChern-Hooi Lim , Max Kudisch, Bin Liu, and Garret M. MiyakeC –N cross-coupling is an important class of reactions with far-reaching impacts across chemistry, materials science, biology, and medicine. Transition metal complexes can elegantly orchestrate diverse aminations but typically require demanding reaction conditions, precious metal catalysts, or oxyge n-sensitive procedures. Here, we introduce a mild nickel-catalyzed C–N cross-coupling methodology that operates at room temperature using an inexpensive nickel source (NiBr2·3H2O), is oxygen tolerant, and proceeds through direct irradiation of the nickel –amine complex. 
Source: Organometallic Current - Category: Chemistry Tags: C-N Bond Forming Ni Catalyzed Photoredox Catalysis Source Type: blogs