Evaluating the expression of cyclooxygenase-2 enzyme by immunohistochemistry in normal and tumoral tissue before and after neoadjuvant chemoradiotherapy in patients with esophageal cancer in Khorasan Province
Conclusions: The results indicated that expression of COX-2 in tumoral tissues exceeds the expression of COX-2 in normal tissue of the baseline biopsy. Patients with a high expression of COX-2 in baseline tumor biopsies had less response to treatment of pathology compared to patients with lower expression of COX-2 in baseline tumor biopsies.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Yousef Jalalabadi Alireza Shirazi Mohammad-Reza Ghavam-Nasiri Seyed Amir Aledavood Dariush Sardari Bahram Memar Soodabeh Shahidsales Fatemeh VarshoeeTabrizi Parvane Dehghan Hassan Vosughiniya Source Type: research
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