Corneal Stiffness and Its Relationship With Other Corneal Biomechanical and Nonbiomechanical Parameters in Myopic Eyes of Chinese Patients

Purpose:
To investigate corneal stiffness and analyze its possible influence on other corneal biomechanical and nonbiomechanical parameters in myopic eyes of Chinese patients.
Methods:
A total of 387 healthy (right) myopic eyes were included in this study. Corneal visualization Scheimpflug technology was used to measure the corneal stiffness parameter at the first applanation (SP-A1), deformation amplitude ratio at 1.0 and at 2.0 mm, biomechanically corrected intraocular pressure (bIOP), and corneal deformation parameters during the first applanation (A1: A1-time, A1-length, and A1-velocity), second applanation (A2; A2-time, A2-length, and A2-velocity), and highest concavity (HC; HC-time, HC-radius, HC deformation amplitude, and HC peak distance). The Pentacam was used to evaluate central corneal thickness, mean corneal curvature (Km), anterior corneal central elevation, and corneal asphericity (Q value) of the anterior cornea.
Results:
The mean SP-A1 and bIOP values were 90.46 ± 15.39 mm Hg/mm and 13.5 ± 1.85 mm Hg, respectively. The SP-A1 increased with age (β = 0.41 [95% CI, 0.28%–0.54%]; P

Source: Cornea - June 11, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research