Comparison of GLUT-1, SGLT-1, and SGLT-2 expression in false-negative and true-positive lymph nodes during the 18F-FDG PET/CT mediastinal nodal staging of non-small cell lung cancer

The treatment options for non-small cell lung cancer (NSCLC) are based mainly on cancer stage. Surgery is the historical gold standard for stages without mediastinal lymph node involvements (stages Ⅰ and Ⅱ), while a combination of chemotherapy and radiation therapy is used for patients with mediastinal lymph node metastasis (stage Ⅲ), although in some cases, a combination of surgery and neoadjuvant therapy is considered [1,2]. Therefore, the accurate staging of mediastinal lymph nodes in patients with NSCLC is of paramount importance.

Source: Lung Cancer - June 9, 2018 Category: Cancer & Oncology Authors: Naohiro Taira, Eriko Atsumi, Saori Nakachi, Reika Takamatsu, Tomofumi Yohena, Hidenori Kawasaki, Tsutomu Kawabata, Naoki Yoshimi Source Type: research