Metformin safe for most diabetics with kidney disease

Metform, a longtime and low-cost drug used to treat diabetes, is safe for most patients who also have chronic kidney disease, according to new research.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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We’re excited to share the topic and questions for this week’s #HITsm chat happening Friday, 8/24 at Noon ET (9 AM PT). This week’s chat will be hosted by Colton Ortolf (@ColtonOrtolf) who blogs at tech prescribed on the topic of “The Role of Technology in Chronic Disease Management“. Chronic disease is an incredibly broad term, but it can be simply defined as “a physical or mental health condition that lasts more than one year and causes functional restrictions or requires ongoing monitoring or treatment.” In all, 86% of $2 trillion in US healthcare expenditures eac...
Source: EMR and HIPAA - Category: Information Technology Authors: Tags: #HITsm Digital Health Healthcare HealthCare IT #HITsm Topics Chronic Care Management Chronic Disease Management Colton Ortolf tech prescribed Source Type: blogs
Publication date: Available online 20 June 2018Source: Canadian Journal of DiabetesAuthor(s): Stephany I. Adame Perez, Peter A. Senior, Catherine J. Field, Kailash Jindal, Diana R. MagerAbstractObjectivesFrailty can cause increased vulnerability to adverse health outcomes, such as falls, fractures, depression and reduced health-related quality of life (HRQoL). This cross-sectional study compared the differences in body composition, HRQoL, mental health and cognitive and vitamin D (vitD) status with health-care utilization by frail and nonfrail adults with diabetes mellitus (type 1 and type 2) and with chronic kidney diseas...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Authors: Kim KS, Park SW, Cho YW, Kim SK Abstract BACKGROUND: To evaluate the prevalence of chronic kidney disease (CKD) and progression rate to CKD in elderly patients with type 2 diabetes mellitus (T2DM). METHODS: We investigated the medical records of 190 elderly patients (65 years or older) with T2DM from 2005 to 2011 in 6-month increments. Mean follow-up duration was 64.5 months. CKD was defined as estimated glomerular filtration rate (eGFR)
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
Publication date: Available online 16 August 2018Source: American Journal of Kidney DiseasesAuthor(s): Maria L. Gonzalez Suarez, Andrea Kattah, Joseph P. Grande, Vesna GarovicAs the incidence of chronic kidney disease increases and women pursue pregnancy at more advanced ages, the management of kidney disease in pregnancy has become increasingly relevant to the practicing nephrologist. Women with kidney disorders face several challenges in pregnancy due to increased physiologic demands on the kidney and risk for disease progression, the potential teratogenicity of medications, and the increased risk for complications such ...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
A morbidly-obese 57-year-old diabetic and hypertensive man with chronic kidney disease, diastolic heart failure, and bilateral hearing loss was found to have soft tissue masses/densities in the lateral aspect of both auditory canals on local examination and on imaging. He underwent biopsies of both ear canal masses and histologic examination revealed amyloid deposits in the dermis. These deposits were confirmed as AL (amyloid light chain) kappa-type amyloid by laser mass spectrometry. A systemic work-up showed plasma cell dyscrasia with 9% kappa light chain restricted plasma cells in the bone marrow as well as amyloid depo...
Source: Otology and Neurotology - Category: ENT & OMF Tags: Temporal Bone Histopathology Case of the Month Source Type: research
Conclusion IgAVN in elderly patients is characterized by severe renal involvement. Elderly patients are at higher risk than adults for treatment-related adverse events. PMID: 30101942 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Abstract Diabetic kidney disease (DKD), one of the most common and severe microvascular complications of diabetes, is the leading cause of chronic kidney disease and end-stage kidney disease worldwide. Since the development of renin-angiotensin system inhibition nearly three decades ago, no new therapeutic agents have received regulatory approval for treatment of DKD. Glucagon like peptide-1 (GLP-1) receptor agonists, a class of newer anti-hyperglycemic agents, have shown promise for prevention of DKD onset and progression. This perspective summarizes clinical and experimental observations to give insight into bio...
Source: Am J Physiol Renal P... - Category: Urology & Nephrology Authors: Tags: Am J Physiol Renal Physiol Source Type: research
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Source: Hospital Practice - Category: Hospital Management Authors: Source Type: research
In this issue ofJAMA, Webster and colleagues report the results of the Triple Pill vs Usual Care Management for Patients with Mild-to-Moderate Hypertension (TRIUMPH) pragmatic randomized clinical trial that evaluated the efficacy of a low-dose combination pill containing 20 mg of telmisartan, 2.5 mg of amlodipine, and 12.5 mg of chlorthalidone compared with usual care among 700 adults with hypertension in Sri Lanka. The primary outcome was the proportion of patients whose blood pressure (BP) was controlled at 6 months, which was defined as a systolic/diastolic BP of less than 140/90 mm Hg or less than 130/80 mm Hg among pa...
Source: JAMA - Category: General Medicine Source Type: research
The aim of the study was to improve the frequency of diagnosing chronic kidney disease (CKD) in seniors with diabetes. Less than 10% of those with stages 2 or 3 CKD and less than 50% with stage 4 CKD know they have renal impairment. A pre-post study design was implemented in 2 primary care facilities. The study sample was 222 older adults aged> 55 years with diabetes. A medical record audit verified the number of patients diagnosed with CKD doubled from 16 preintervention to 32 postintervention (P  = .014).
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Featured Article Source Type: research
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