Aberrant expression of stress-induced phosphoprotein 1 in colorectal cancer and its clinicopathologic significance
Stress-Inducible Phosphoprotein1 (STIP1) is an adaptor protein that bridges HSP70 and HSP90 folding and a secretory protein that regulates malignant tumor progression. The aim of the present study was to demonstrate the clinicopathological significance and prognostic role of STIP1 in colorectal cancer (CRC). We used data from The Cancer Genome Atlas (TCGA) to analyze STIP1 expression in CRC and utilized 8 pairs of fresh-frozen tissue samples to investigate STIP1 expression in CRC tissues and adjacent normal tissues using quantitative real-time polymerase chain reaction (qRT-PCR) and western blot assays.
Source: Human Pathology - Category: Pathology Authors: Zhimei Zhang, Hui Ren, Liang Yang, Xinhua Zhang, Wei Liang, Hui Wu, Leilei Huang, Jihui Kang, Jianbo Xu, Ertao Zhai, Shirong Cai, Yulong He Tags: Original Contributions Source Type: research