Glutamatergic Biomarkers for Cocaine Addiction: A Longitudinal Study Using MR Spectroscopy and mGluR5 PET in Self-Administering Rats

Conclusion: Baseline values of prefrontal glutamate and glycine are associated with future cocaine use. Furthermore, baseline rIGT scores are associated with both sucrose and cocaine. Finally, both glutamate concentration and mGluR5 availability decrease during exposure to cocaine.

Source: Journal of Nuclear Medicine - June 1, 2018 Category: Nuclear Medicine Authors: de Laat, B., Weerasekera, A., Leurquin-Sterk, G., Bormans, G., Himmelreich, U., Casteels, C., Van Laere, K. Tags: Basic Source Type: research