Outcome of Primary Nonpenetrating Deep Sclerectomy in Patients with Steroid-Induced Glaucoma.

Conclusion: Primary nonpenetrating deep sclerectomy is a safe and an effective method of treating eyes with steroid-induced glaucoma. No major complications were encountered. After 4 years of follow-up, complete success rate was 56.7% and qualified success rate was 70%. PMID: 29850218 [PubMed]
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research

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CONCLUSION: If the progression of the disease is noticeable in patients with glaucoma at follow-up, night-time hypotension should be ruled out with ambulatory blood pressure and if this is observed medical treatments used by the patients should be reviewed and necessary measures should be taken. PMID: 30650042 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
In this study, we aimed to investigate the potential role and regulatory mechanism of SIRT6 in hydrogen peroxide (H2O2)-induced oxidative damage of RGCs in vitro. We found that SIRT6 expression was significantly downregulated in RGCs with H2O2 treatment. Functional experiments showed that overexpression of SIRT6 improved survival and reduced apoptosis and the production of reactive oxygen species (ROS) in H2O2-treated RGCs. In contrast, SIRT6 knockdown had the opposite effect. Moreover, we found that SIRT6 overexpression promoted the nuclear accumulation of nuclear factor erythroid 2-related factor 2 (Nrf2) and increased t...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
The Glaucous Gull (Larus hyperboreus) is the world’s second largest gull (largest is the Great Black-backed Gull (Larus marinus). It breeds in The Arctic but we do see them further south. My photograph is of a first winter youngster. It is feeding on seal blubber on the beach way East of the beach carpark at Cley-next-the-sea in North Norfolk (we saw a few dead seals on the beach on this visit perhaps battered in yesterday’s high winds and rough seas). The word “glaucous” is descriptive of the adult bird’s colour. It simply means “dull bluish-green, gray,” but somehow that came fr...
Source: David Bradley Sciencebase - Songs, Snaps, Science - Category: Science Authors: Tags: Sciencebase Source Type: blogs
Authors: Zhu S, Wang D, Han J Abstract Objective: A prospective study was performed to observe the effects of nonsteroidal anti-inflammatory drug (NSAID) eyedrops on intraocular pressure (IOP) and the ocular surface in primary open-angle glaucoma (POAG) patients treated with 0.005% latanoprost eyedrops. Methods: Forty-eight subjects were randomized into two study groups (NSAID and control). Latanoprost was continued for 10 weeks in all subjects. At the end of week 4, pranoprofen was added in the NSAID group, and treatment lasted for 4 weeks, whereas patients in the control group were treated with latanoprost al...
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Authors: Lau CSL, Chan JCW, So SF, Chan OCC, Li KKW Abstract Purpose: To compare the surgical outcome of combined phacoemulsification and endoscopic cyclophotocoagulation (phacoECP) versus combined phacoemulsification and mitomycin C-augmented trabeculectomy (phacoTbx) in patients with coexisting glaucoma and visually significant cataract. Methods: A retrospective review of 89 eyes of 89 patients who received phacoECP (N=49) and phacoTbx (N=40) was carried out at a tertiary eye center in Hong Kong. The minimum follow-up period was 6 months. Criterion of success was reduction of IOP at least 30% or absolute IOP ...
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension Intervention:   Drug: Netarsudil Ophthalmic Solution 0.02% Sponsor:   Aerie Pharmaceuticals Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Glaucoma Intervention:   Procedure: combined glaucoma surgery Sponsor:   Medical University of Bialystok Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Glaucoma, Open-Angle;   Ocular Hypertension Intervention:   Drug: Netarsudil Ophthalmic Solution 0.02% Sponsor:   Aerie Pharmaceuticals Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Glaucoma Intervention:   Procedure: combined glaucoma surgery Sponsor:   Medical University of Bialystok Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
OBJECTIVE: To determine where glaucoma patients most often fall and how integrated visual field (IVF) damage affects falls rates per year (falls/year) and per step (falls/step) at and away from home. DESIGN: Prospective, observational cohort study ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
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