Lipopolysaccharide Preconditioning Increased the Level of Regulatory B cells in the Spleen after Acute Ischaemia/Reperfusion in Mice.

CONCLUSIONS: I/R mice preconditioned with LPS showed significantly reduced pathological damage, motor dysfunction, cognitive dysfunction, and inflammatory responses. LPS PC may initiate anti-inflammatory protective mechanism in the spleen after stroke, may increase the number of anti-inflammatory cells, such as Bregs, in the spleen, and may play a protective role in stroke.
PMID: 29803621 [PubMed - as supplied by publisher]

Source: Brain Research - May 24, 2018 Category: Neurology Authors: Wang Z, Zhou Y, Yu Y, He K, Cheng LM Tags: Brain Res Source Type: research