Preoperative radiotherapy or chemoradiotherapy in rectal cancer - Is survival improved? An update of the "Nordic" LARC study in non-resectable cancers.

Preoperative radiotherapy or chemoradiotherapy in rectal cancer - Is survival improved? An update of the "Nordic" LARC study in non-resectable cancers. Radiother Oncol. 2018 May 16;: Authors: Brændengen M, Glimelius B Abstract The randomized "Nordic" LARC study compared preoperative long-course radiotherapy alone (RT) or with chemotherapy (CRT) in the most locally advanced/ugly rectal cancers. Despite significantly better local control in the CRT group, no overall survival benefit was seen after 10 years follow-up. The relations between local control and survival are discussed. PMID: 29778486 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29778486?dopt=Abstract

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - May 16, 2018 Category: Radiology Authors: Brændengen M, Glimelius B Tags: Radiother Oncol Source Type: research