Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer ’s disease

Disease-associated-microglia (DAM) represent transcriptionally-distinct and neurodegeneration-specific microglial profiles with unclear significance in Alzheimer ’s disease (AD). An understanding of heterogenei...

Source: Molecular Neurodegeneration - May 21, 2018 Category: Neurology Authors: Srikant Rangaraju, Eric B. Dammer, Syed Ali Raza, Priyadharshini Rathakrishnan, Hailian Xiao, Tianwen Gao, Duc M. Duong, Michael W. Pennington, James J. Lah, Nicholas T. Seyfried and Allan I. Levey Tags: Research article Source Type: research