Brain-derived microparticles activate microglia/macrophages and induce neuroinflammation.

In this study, we used flow cytometry, hopping probe ion conductance microscopy, immunofluorescence and other techniques to study the effect of brain-derived microparticle activation on microglia/macrophages that leads to neuroinflammation. BDMPs might be possible targets for the treatment of traumatic brain injury (TBI) changes after secondary nerve inflammation.
PMID: 29777675 [PubMed - as supplied by publisher]

Source: Brain Research - May 16, 2018 Category: Neurology Authors: Rong H, Fan Y, Yang M, Zhang B, Sun D, Zhao Z, Wang D, Fan W, Wang J, Gu G, Li F, Liu X, Rao C, Chen H, Wang Y, Tian Y, Zhang J Tags: Brain Res Source Type: research