5. Modeling Synovial Sarcoma from initiation through metastasis
Synovial Sarcoma is the most common soft tissue sarcoma in adolescents and young adults. The prognosis for patients that have acquired metastatic synovial sarcoma is poor. We have been able to model this neoplastic in mice and the disease mirrors human sarcoma, histologically and molecularly. PTEN appears to be a major driver to metastasis.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Mario Capecchi Source Type: research
More News: Cancer | Cancer & Oncology | Cancer in Adolescents | Cancer in Young Adults | Genetics | Sarcomas | Soft Tissue Sarcoma | Synovial Sarcoma