High-resolution melting PCR analysis for rapid genotyping of Burkholderia mallei.

In this study, we designed a high-resolution melting (HRM) method for the screening of 15 phylogenetically informative SNPs within the genome of B. mallei that subtype the species into 3 lineages and 12 branches/sub-branches/groups. The present results demonstrate that SNP-based genotyping represent an interesting approach for the molecular epidemiology analysis of B. mallei. PMID: 29751195 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29751195?dopt=Abstract

Source: Infection, Genetics and Evolution - May 8, 2018 Category: Genetics & Stem Cells Authors: Girault G, Wattiau P, Saqib M, Martin B, Vorimore F, Singha H, Engelsma M, Roest HJ, Spicic S, Grunow R, Vicari N, De Keersmaecker SCJ, Roosens NHC, Fabbi M, Tripathi BN, Zientara S, Madani N, Laroucau K Tags: Infect Genet Evol Source Type: research