Modification of apparent intracerebral hematoma volume on T2 ∗-weighted images during normobaric oxygen therapy may contribute to false diagnosis

Publication date: June 2018 Source:Journal of Clinical Neuroscience, Volume 52 Author(s): Romain Goulay, Antoine Drieu, Camille Di Palma, Palma Pro-Sistiaga, Nicolas Delcroix, Laurent Chazalviel, Romaric Saulnier, Clément Gakuba, Suzanne Goursaud, Allan R. Young, Maxime Gauberti, Cyrille Orset, Evelyne Emery, Denis Vivien, Thomas Gaberel It was previously reported that normobaric oxygen therapy (NBO) significantly affected T2∗-weighted imaging in a mouse model of intracerebral hemorrhage (ICH). However, it is unclear whether a similar phenomenon exists in large volume ICH as seen in human pathology. We investigated the effects of NBO on T2∗-weighted images in a pig model of ICH. Our data show that NBO makes disappear a peripheral crown of the hematoma, which in turn decreases the apparent volume of ICH by 18%. We hypothesized that this result could be translated to ICH in human, and subsequently could lead to inaccurate diagnostic.
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research