Evidence from animal models on the pathogenesis of PCOS

Polycystic ovarian syndrome (PCOS) is the most common endocrine condition in women, and is characterized by reproductive, endocrine and metabolic features. However, there is no simple unequivocal diagnostic test for PCOS, its etiology remains unknown and there is no cure. Hence, the management of PCOS is suboptimal as it relies on the ad hoc empirical management of its symptoms only. Decisive studies are required to unravel the origins of PCOS, but due to ethical and logistical reasons these are not possible in humans.

Source: Best Practice and Research. Clinical Endocrinology and Metabolism - March 31, 2018 Category: Endocrinology Authors: K.A. Walters, M.J. Bertoldo, D.J. Handelsman Tags: 1 Source Type: research