Could reading our circadian clocks according to DNA repair optimize chemotherapy?

(University of North Carolina Health Care) For the first time, the lab of Nobel laureate Aziz Sancar measured DNA repair after cisplatin treatment throughout the entire genome of a mammal over the 24-hour circadian cycle. They found DNA repair of normal tissue was most robust predawn and pre-dusk in mice, and these could represent the best times for treatment using the anti-cancer drug cisplatin, though much more work needs to be done.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news