The mutational analysis in the diagnostic work-up of thyroid nodules: the real impact in a center with large experience in thyroid cytopathology

ConclusionsOur study established mutational rates forBRAF andRAS genes in a large series of FNA specimens.BRAF mutations were confirmed as highly specific but not able to improve cytological diagnosis, whileRAS testing proved effective in assessing malignancy in nodules with indeterminate and benign cytology.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research