Altered proteomic profile in umbilical arterial serum from mothers with schizophrenia

Schizophrenia is known to be a multi-factorial disease caused by genetic and environmental factors. Accumulating evidence has demonstrated that intrauterine exposure to inflammation (maternal immune activation; MIA) subsequently leads to psychiatric diseases, including schizophrenia, owing to fetal programming (Estes and McAllister, 2016). Previous proteomic analysis of saliva revealed that proteins involved in innate immunity are increased in subjects with schizophrenia (Iavarone et al., 2014).
Source: Schizophrenia Research - Category: Psychiatry Authors: Tags: Letter to the Editor Source Type: research