[Correspondence] Embolic strokes of undetermined source: support for a new clinical construct–Authors' reply

The interesting and important observations summarised by Pascal Gratz and colleagues lend support to the embolic strokes of undetermined source (ESUS) construct developed in our recent Personal View. Two large, international randomised trials are underway that will compare new oral anticoagulants (dabigatran and rivaroxaban, respectively) with aspirin for secondary stroke prevention in ESUS cohorts, and assess the therapeutic implications of this novel construct. Finally, cryptogenic (of unknown cause) stroke will be the subject of these long-overdue, randomised trials that will shed light on this obscure, but common, entity.

Source: Lancet Neurology - September 16, 2014 Category: Neurology Authors: Robert G Hart, Hans-Christoph Diener, Stuart J Connolly Tags: Correspondence Source Type: research