Odorant Item Specific Olfactory Identification Deficit May Differentiate Alzheimer's Disease From Aging

• Screening for amnestic disorder must differentiate from changes associated with normal aging.• Using an odorant identification test, we identified specific odorants which failure to identify best predicts amnestic disorder vs. normal aging. The identified odorants were validated with performan ce on neuropsychological testing and prediction of conversion from amnestic mild cognitive impairment to Alzheimer's disease.• Olfactory identification impairment was associated with poor performance in numerous cognitive domains and was predictive of progression of mild cognitive impairment.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Regular Research Articles Source Type: research