Simplification of first-line antibacterial regimen for complicated appendicitis in children was associated with better adherence to guidelines, and reduced use of antibiotics

Acute appendicitis is a common surgical condition that affects 0.3-0.4% of children, with a peak incidence between 8 and 13 years. Most common complications include perforation, peritonitis, and abscess, found in 25-39% of cases [1]. Treatment of acute appendicitis usually relies on early surgery (appendectomy, and management of complications when necessary), and a short course of antibiotics (4-7 days) [2], although highly selected patients with a well circumscribed focus of infection may be cured by antimicrobial therapy alone [3].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Short Communication Source Type: research