Current Multidisciplinary Approach to Fertility Preservation for Breast Cancer Patients.

Current Multidisciplinary Approach to Fertility Preservation for Breast Cancer Patients. Acta Med Okayama. 2018 Apr;72(2):137-142 Authors: Takahashi Y, Shien T, Sakamoto A, Tsuyumu Y, Yoshioka R, Uno M, Hatono M, Kochi M, Kawada K, Tsukioki T, Iwamoto T, Ikeda H, Taira N, Matsuoka J, Nakatsuka M, Doihara H Abstract Adverse effects on fertility are a significant problem for premenopausal breast cancer patients. Since April 2009, we have been referring young patients for fertility counseling provided by a multidisciplinary team. Here we evaluated the efficacy and safety of our current fertility preservation approach. We retrospectively analyzed the cases of 277 patients < 45 years old at diagnosis, which was made between 2009 and 2016. Seventy-two (26%) patients received fertility counseling. Seventeen (6%) of the 277 patients decided to preserve their fertility before starting adjuvant systemic therapy. Six (35%) patients underwent oocyte cryopreservation, and 11 (65%) married patients opted for embryo cryopreservation. There were no pregnancies among the patients undergoing oocyte cryopreservation, whereas 3 (27%) of the patients who opted for embryo cryopreservation became pregnant. Two (12%) patients stopped endocrine therapy after 2 years in an effort to become pregnant, but their breast cancers recurred. Though the problem of fertility loss for breast cancer patients is important and we should assess the infertility risk for a...
Source: Acta Med Okayama - Category: Universities & Medical Training Authors: Tags: Acta Med Okayama Source Type: research