Impact and Assessment of Sleep Disturbance in Adults and Children with Allergic Rhinitis

AbstractPurpose of ReviewIn this article, we review the impact and the treatment of sleep disturbance caused by allergic rhinitis (AR) in adult and pediatric patients.Recent FindingsAlthough intranasal corticosteroids (INS) remain the mainstay treatments for AR-induced sleep disturbance, allergen immunotherapy (AIT) has been suggested to be effective in altering the course and progression of moderate-to-severe AR that is refractory to pharmacotherapy. MP-AzeFlu is a recently developed formulation containing azelastine, an intranasal antihistamine (INAH), and fluticasone propionate, an INS. MP-AzeFlu has been reported to have a fast onset of action thanks to the effect of the INAH.SummaryAR is one of the most common chronic inflammatory diseases in the USA with symptoms that can severely affect patients ’ quality of life. Sleep disturbance is a serious consequence of AR-induced symptoms that can lead to daytime somnolence, impaired cognitive functions, and decreased work/school performance. Nasal congestion and rhinorrhea have been suggested to be the primary causes of sleep disturbance in patien ts with AR. There is a lack of adequate assessment method for AR-induced sleep disturbance and its consequences in the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines and the Sino-Nasal Outcome Test-22 (SNOT-22). The NIH-developed Patient Reported Outcome Measurement Information System (PROMIS) has measures for these symptoms. Although more research is needed to develop...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research