Correspondence Adverse pregnancy outcomes due to Chlamydia trachomatis
Joanne Reekie and colleagues1 did a population-based cohort study on the association between a positive test for chlamydia and spontaneous preterm birth, having a baby who is small for gestational age, or stillbirth. On the basis of the findings from their study, the authors concluded that a genital chlamydia infection —presumably treated either before or during pregnancy, regardless of the trimester during which testing occurred—does not substantially increase a woman's risk of having one of these three adverse pregnancy outcomes.
Authors: D'Aiuto C, Valderrama A, Byrns M, Boucoiran I Abstract OBJECTIVES: To analyze risk factors for the presence of sexually transmitted and blood-borne infections (STBBIs) in pregnancy and to determine whether pregnant women with STBBIs are more likely to experience adverse pregnancy outcomes. METHODS: This retrospective cohort study involved analyzing the electronic records of 3460 pregnant women followed at Sainte-Justine Hospital in Montréal, Québec, between March 2017 and January 2019. An outcome is defined as a pregnancy where the woman has at least one positive laboratory result for chl...
The most common known causes of female infertility are male factor (26%), ovulatory failure (21%), and tubal damage (14%), while in 28% a couple ’s infertility remains unexplained. Female-specific causes of infertility include deterioration of oocyte quality with increasing maternal age; ovulatory disorders, most notably polycystic ovarian syndrome; history of salpingitis such as that caused by chlamydia infection; endometriosis; and uteri ne cavity abnormalities interfering with implantation causing inability to become pregnant or causing recurrent pregnancy loss.
Authors: Peng L, Chen JL, Wang D Abstract Worldwide, genital infection with Chlamydia trachomatis (C. trachomatis) is one of the most common sexually transmitted infections. Most infections are asymptomatic. However, particularly in women, untreated infection with C. trachomatis can lead to complications that include pelvic inflammatory disease, infertility, and tubal ectopic pregnancy. Rapid methods for early and accurate diagnosis for infection with C. trachomatis that can be performed in the clinic would allow for earlier treatment to prevent complications. Traditional laboratory-based tests for C. trachomatis i...
We examined the prevalence and impact of STIs (gonorrhea, chlamydia, and trichomonas) on PTB and chorioamnionitis in pregnant adolescents. Methods: This retrospective cohort study utilized the first pregnancy delivered at an urban hospital among patients ≤ 19 years old over a 5-year period. Poisson regression with robust standard errors was used to estimate prevalence ratios (PR) and 95% confidence intervals (CI) of the association between STIs and PTB (
Abstract OBJECTIVE: To identify factors associated with testing for and diagnosis of trichomoniasis in pregnancy and to describe patterns of treatment and tests of reinfection or persistence. METHODS: We conducted a retrospective cohort study of women who delivered from July 2016 to June 2018 at one institution. Testing for Trichomonas vaginalis infection was done by wet mount microscopy or by nucleic acid amplification testing for routine prenatal testing or symptomatic visits. Poisson regression was used to identify factors associated with testing for trichomoniasis and testing positive in pregnancy. Treatm...
ConclusionsTaking modelling assumptions into account, opportunistic chlamydia and gonorrhoea screening of youth and those in HIV care represents a viable intervention for reducing sexually transmitted infections in the South African population.
Current Canadian guidelines for adolescent obstetrical care recommend sexually transmitted infection (STI) screening at entry to care and in the third trimester. Our study assessed the rate of new and recurrent Chlamydia trachomatis (CT) and Neisseria gonorrhea (NG) infections in the third trimester at an adolescent obstetrics clinic. We hypothesized that targeted repeat screening may be appropriate in this adolescent population.
This study determined if prenatal C. trachomatis infection is associated with preterm birth (PTB) and preeclampsia subtypes. Methods A retrospective cohort study was conducted using 22,772 singleton pregnancies with a prenatal C. trachomatis diagnostic test. Spontaneous and medically indicated PTBs, and term and preterm preeclampsia were outcomes. Modified Poisson regression calculated relative risk (RR) and 95% confidence intervals (CI) with propensity score adjustments stratified by maternal ages
CONCLUSION: Traditional risk factors are associated with increased risk of infection during pregnancy. Prenatal care adequacy and insurance status were associated with the likelihood of being tested. Delays in treatment and tests of reinfection were common. Point-of-care testing and expedited partner therapy should be explored as ways to improve the management of these infections in pregnancy. PMID: 32168225 [PubMed - as supplied by publisher]
Authors: López-Corbeto E, González V, Casabona J, Grupo de estudio CT NG PMID: 32143940 [PubMed - as supplied by publisher]