Pre ‐anthracycline echocardiogram rarely changes treatment strategy in acute myeloid leukemia
American Journal of Hematology, EarlyView.
Cancer Medicine, EarlyView.
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Recurrent Acute Myeloid Leukemia; Refractory Acute Myeloid Leukemia; TP53 Gene Mutation Negative Interventions: Drug: Cytarabine; Drug: MDM2 Inhibitor DS-3032b Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI) Not yet recruiting
With the recent maturation of novel therapies for acute myeloid leukemia (AML), the field of AML therapeutics is rapidly progressing. In this interview, Farhad Ravandi, MD, from the University of Texa... Author: VJHemOnc Added: 08/16/2018
Graft-versus-leukaemia effect post fludarabine, melphalan and alemtuzumab reduced intensity allogeneic stem cell transplantat in HIV-infected patient with acute myeloid leukaemia, Published online: 16 August 2018; doi:10.1038/s41409-018-0297-zGraft-versus-leukaemia effect post fludarabine, melphalan and alemtuzumab reduced intensity allogeneic stem cell transplantat in HIV-infected patient with acute myeloid leukaemia
Conditions: Acute Myeloid Leukemia; Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Chronic Myelomonocytic Leukemia; Myelodysplastic Syndrome; Myelodysplastic/Myeloproliferative Neoplasm; Secondary Acute My eloid Leukemia Interventions: Drug: Edetate Calcium Disodium; Dietary Supplement: Multivitamin; Drug: Succimer Sponsors: M.D. Anderson Cancer Center; Nationa...
There has been an influx of novel therapies within the field of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Here, Eunice Wang, MD, of Roswell Park Comprehensive Cancer Center, Bu... Author: VJHemOnc Added: 08/15/2018
Cortisol is a key activator in a pathway that enables acute myeloid leukaemia cells to evade the immune system, according to a study published inCellular& Molecular Immunology.Science Daily
We describe the first case of histologically-confirmed NEC caused by S. maltophilia accompanied by bacteremia and pneumonia after salvage chemotherapy for acute myeloid leukemia relapse following a second hematopoietic stem cell transplantation. S. maltophilia should be included as a pathogenic organism of NEC in severely immunocompromised patients to prevent a delayed diagnosis, which carries a high risk of inappropriate antimicrobial selection and fatal outcome. PMID: 30101922 [PubMed - as supplied by publisher]
Acute myeloid leukemia (AML) is a heterogeneous hematopoietic malignancy characterized by an aberrant clonal expansion of undifferentiated myeloid blasts. Studies have shown that leukemia stem cells (LSCs) contribute to relapse after chemotherapeutic treatment.  Like normal hematopoietic stem cells (HSCs), LSCs maintain their self-renewal ability while generating clonogenic leukemic progenitors capable of producing leukemic cells . Anti-proliferative chemotherapeutic agents commonly target the rapidly cycling leukemic cells, but they generally are ineffective against the quiescent LSCs, partly because of enhanced dru...
Authors: Lamba JK, Cao X, Raimondi SC, Rafiee R, Downing JR, Shi L, Gruber T, Ribeiro RC, Rubnitz JE, Pounds SB Abstract [This corrects the article DOI: 10.18632/oncotarget.25475.]. PMID: 30101002 [PubMed - in process]