Vascular oxidative stress upregulates angiotensin II type I receptors via mechanisms involving nuclear factor kappa B.

In conclusion, vascular oxidative can upregulate AT1R, via mechanisms involving NFκB, and contribute to the development of hypertension. PMID: 25198883 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/25198883?dopt=Abstract

Source: Clinical and Experimental Hypertension - September 14, 2014 Category: Cardiology Authors: Bhatt SR, Lokhandwala MF, Banday AA Tags: Clin Exp Hypertens Source Type: research

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