Rituximab in Refractory Chronic Spontaneous Urticaria: An Encouraging Therapeutic Approach

Conclusion: Rituximab is a chimeric murine/human monoclonal antibody directed against CD20, which depletes memory B-lymphocytes that are necessary for autoantibody production. The abrogation of the autoantibody production is the proposed mechanism by which it may alleviate the symptoms of CSU.Skin Pharmacol Physiol 2018;31:184 –187
Source: Skin Pharmacology and Physiology - Category: Dermatology Source Type: research