Clinical and Endoscopic Remission in a Patient With Cronkhite-Canada Syndrome

A 60-year-old man presented with chronic diarrhea for 9 months, anorexia, a 6-kg weight loss, and dysgeusia. He had hyperpigmentation of his  face, hands (Figure A), and feet; alopecia; and nail dystrophy (Figure A). An esophagogastroduodenoscopy and a colonoscopy showed multiple polyps carpeting the stomach, duodenum, ileum, and the colon (Figure B). Histology showed cystically dilated glands and mixed inflammatory infiltrate comprisin g eosinophils and neutrophils. Cronkhite–Canada syndrome was diagnosed on the basis of clinical and pathologic findings.

Source: Clinical Gastroenterology and Hepatology - April 5, 2018 Category: Gastroenterology Authors: Saurabh Dawra, Vishal Sharma, Usha Dutta Tags: Electronic Image of the Month Source Type: research