[Transplantation strategy in type 1 diabetic patients].
[Transplantation strategy in type 1 diabetic patients].
Nephrol Ther. 2018 Apr;14 Suppl 1:S23-S30
Authors: Buron F, Badet L, Morelon E
Abstract
Beta cell replacement by pancreas or Langerhans islets transplantation is the only way to restore glucose homeostasis in type 1 diabetic patients. The counterpart is the need for long-term immunosuppression. These transplantations are therefore mainly indicated for patients candidates for kidney transplantation and for patients with poor quality of life due to unstable diabetes with life-threatening hypoglycemic events. Both beta cell replacement techniques have different benefits and risks and should be adapted to each type 1 diabetic patient. The transplant strategy must be personalized according to parameters assessed in the pre-transplant period, validated by a multidisciplinary team and reassessed regularly until transplantation.
PMID: 29606260 [PubMed - in process]
Source: Nephrologie and Therapeutique - Category: Urology & Nephrology Authors: Buron F, Badet L, Morelon E Tags: Nephrol Ther Source Type: research
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