Gene Variants Tied to Albuterol Response in Minority Kids With Asthma Gene Variants Tied to Albuterol Response in Minority Kids With Asthma
A new genome-wide association study has identified variants associated with worse albuterol response in African American and Puerto Rican children with asthma.Reuters Health Information
PMID: 32448438 [PubMed - in process]
PMID: 32448437 [PubMed - in process]
Daily in - bedroom use of a PM2.5 filter results in significant improvement of airway mechanics
The 2020 Members of Proficiency Standards for Pulmonary Function Testing Committee of the American Thoracic Society recently raised concerns on pulmonary function testing (PFT) “as a potential avenue for COVID 19 transmission due to the congregation of patients with lung disease and because of the potential for coughing and droplet formation”. (1) The Committee reccommen-ded that “PFT be limited to tests that are only essential for immediate treatment decisions” an d that “personal protective equipment (PPE) for healthcare workers should be discussed with local infe-ction control team”.
ConclusionAlthough the clinical benefit of omalizumab in asthma and chronic spontaneous urticaria (CSU) has been established in several clinical trials, there are very little data about its effect on severe VKC. In addition to few previously reported cases we can report the rapid effectiveness of omalizumab in VKC clinically and in terms of quality of life. Randomized trials are needed to include omalizumab in third-line treatment of VKC for prevention of visual impairment and further sequelae such as corneal damage.
Conditions: Allergy; Allergic Asthma; Allergy to Cats; Allergy to House Dust; Allergy to Dog Dander (Finding); Allergy Mold; Allergy Cockroach Intervention: Device: Blood Collection Sponsors: Abionic SA; NAMSA; Johns Hopkins University Not yet recruiting
Peanut allergy (PA) is associated with an economic and psychologic burden on patients and families. Its diagnosis includes tests for peanut specific IgE (sIgE), the values of which usually are categorized as positive or negative using a predefined cutoff (usually 0.35kU/L). With the use of Bayes theorem, this categorization can be replaced with a continuous interpretation if sIgE which accounts for the prevalence of PA and history of ingestion.
Abstract The Patient-Oriented Eczema Measure (POEM, 0-28 points) is a self-assessed, repeatable measurement tool for measuring atopic dermatitis (AD) severity. How-ever, whether POEM score is influenced by allergic comorbidities and whether POEM's severity banding is applicable in web-based surveys for AD remain unclear. A web-based questionnaire survey was conducted in 329 patients with AD. POEM, self-reported severity of AD, and comorbidity of allergic diseases including asthma, pollen rhinitis, allergic conjunctivitis, and food allergy were assessed. POEM scores were not affected by a history of comorbid allerg...
We thank Grigoletto et al for their thoughtful letter regarding our report.1 We agree with the authors ’ conclusion that clinicians should consider history of asthma and asthma control status when managing children with anaphylaxis. In support of their conclusions, the authors cite a study evaluating anaphylactic reactions from peanuts and tree nuts in an outpatient allergy center.2 In contrast to our report, this study includes limited allergens, and may represent a more severe cohort of patients with a higher predilection for asthma and/or severe anaphylaxis based on their referral to an allergy center.