Computer-Aided Antibody Design: An Overview.

Computer-Aided Antibody Design: An Overview.
Adv Exp Med Biol. 2017;1053:221-243
Authors: Choong YS, Lee YV, Soong JX, Law CT, Lim YY
Abstract
The use of monoclonal antibody as the next generation protein therapeutics with remarkable success has surged the development of antibody engineering to design molecules for optimizing affinity, better efficacy, greater safety and therapeutic function. Therefore, computational methods have become increasingly important to generate hypotheses, interpret and guide experimental works. In this chapter, we discussed the overall antibody design by computational approches.
PMID: 29549642 [PubMed - in process]

Source: Advances in Experimental Medicine and Biology - March 22, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research