The D113N mutation in the RING E3 ubiquitin protein ligase gene is not associated with ex vivo susceptibility to common anti-malarial drugs in African Plasmodium falciparum isolates

Plasmodium falciparum resistance to artemisinin-based combination therapy has emerged and spread in Southeast Asia. In areas where artemisinin resistance is emerging, the efficacy of combination is now based on p...

Source: Malaria Journal - March 12, 2018 Category: Infectious Diseases Authors: Mathieu Gendrot, Francis Tsombeng Foguim, Marie Gladys Robert, R émy Amalvict, Joel Mosnier, Nicolas Benoit, Marylin Madamet and Bruno Pradines Tags: Research Source Type: research