GATA3 staining in primary cutaneous apocrine cribriform carcinoma: Usefulness to differentiate it from breast cancer metastasis

ConclusionEven though GATA3 expression has been reported in many benign and malignant adnexal tumors (mostly of sebaceous, follicular, and apocrine differentiation), as well as in many other neoplasms, GATA3 staining to differentiate PCACC from skin breast cancer metastasis has a high negative predictive value. A positive GATA3 staining in this context should permit one to rule out PCACC with a high level of confidence.

Source: Journal of Cutaneous Pathology - March 12, 2018 Category: Pathology Authors: Mar Llamas ‐Velasco, Yosmar C. Pérez‐Gónzalez, Esteban Daudén, Arno Rütten Tags: ORIGINAL ARTICLE Source Type: research