Interplay between COMT Val158Met, childhood adversities and sex in predicting panic pathology: Findings from a general population sample

The single nucleotide polymorphism rs4680 of the catechol-O-methyltransferase (COMT) gene has been implicated to be involved in the etiopathogenesis of panic. However, it remains unresolved whether rs4680 modifies the risk-association between early life stress and subsequent development of panic pathology.

Source: Journal of Affective Disorders - March 8, 2018 Category: Neurology Authors: Eva Asselmann, Johannes Hertel, Katja Beesdo-Baum, Carsten-Oliver Schmidt, Georg Homuth, Matthias Nauck, Hans-J örgen Grabe, Christiane Pané-Farré Tags: Research paper Source Type: research