Moth-eye mimetic cytocompatible bactericidal nanotopography: a convergent design
This study demonstrates
the bactericidal activity and cytocompatibility of the moth-eye mimetic topography produced by
thermal polymer nanoimprinting. The moth-eye topography was found to have bactericidal capabilities
against Gram negative and Gram positive bacteria. Electron microscopy imaging revealed the
bactericidal effect caused by mechanical rupture of the bacteria wall inflicted by the topography on
the adhered cells. The cytocompatibility of the surfaces was evidenced by assessing the
proliferation and morphology of keratinocytes cultured on the nanotopography. The technology meets
important needs in medical implant technology for materials that not only have good biocompatibility
but also antibacterial pro...
Source: Bioinspiration and Biomimetics - Category: Science Authors: Felipe Viela, Iv án Navarro-Baena, Jaime J Hernández, Manuel R Osorio and Isabel Rodríguez Source Type: research