The depth of follicular extension in actinic keratosis correlates with the depth of invasion in squamous cell carcinoma: implication for clinical treatment

ConclusionThe depth of follicular extension of atypical keratinocytes in an AK correlates with the development of depth of invasion of an associated iSCC, irrespective of the pathway of origin. It is therefore important to note the presence and the depth of follicular extension when diagnosing an AK, since follicular extension likely accounts for a significant proportion of recurrent AK and the development of iSCC following superficial treatment modalities.This article is protected by copyright. All rights reserved.

Source: Journal of the European Academy of Dermatology and Venereology - February 28, 2018 Category: Dermatology Authors: M T Fern ández‐Figueras, X Saenz, P Vargas, C T Thompson, C Carrato, L Puig, C Ferrándiz, A Ariza Tags: Original Article Source Type: research