Investigation of short tandem repeats in major depression using whole-genome sequencing data

Major depressive disorder (MDD) is a leading contributor to global disease burden. Recent studies have shown that genetic factors play significant roles in the susceptibility to this condition; however, the underlying genetic basis currently remains largely unknown. Short tandem repeat (STR) has been proposed as an explanatory factor in the “missing heritability” of complex diseases or traits.

Source: Journal of Affective Disorders - February 23, 2018 Category: Neurology Authors: Chenglong Yu, Bernhard T. Baune, Ma-Li Wong, Julio Licinio Tags: Research paper Source Type: research