Strategies to improve recruitment to randomised trials.

CONCLUSIONS: The literature on interventions to improve recruitment to trials has plenty of variety but little depth. Only 3 of 72 comparisons are supported by high-certainty evidence according to GRADE: having an open trial and using telephone reminders to non-responders to postal interventions both increase recruitment; a specialised way of developing participant information leaflets had little or no effect. The methodology research community should improve the evidence base by replicating evaluations of existing strategies, rather than developing and testing new ones.
PMID: 29468635 [PubMed - as supplied by publisher]

Source: Cochrane Database of Systematic Reviews - February 22, 2018 Category: General Medicine Authors: Treweek S, Pitkethly M, Cook J, Fraser C, Mitchell E, Sullivan F, Jackson C, Taskila TK, Gardner H Tags: Cochrane Database Syst Rev Source Type: research