Prognostic and Pathogenic Role of Angiopoietin-1 and -2 in Pneumonia.

CONCLUSIONS: These data suggest a central role of Angiopoietin-1/-2 in pneumonia-evoked inflammation and permeability. Increased Angiopoietin-2 serum levels predicted mortality and length of hospital stay, and Angiopoietin-1 may provide a therapeutic target for severe pneumonia.
PMID: 29447449 [PubMed - as supplied by publisher]

Source: American Journal of Respiratory and Critical Care Medicine - February 15, 2018 Category: Respiratory Medicine Authors: Gutbier B, Neuhauß AK, Reppe K, Ehrler C, Santel A, Kaufmann J, Scholz M, Weissmann N, Morawietz L, Mitchell TJ, Aliberti S, Hippenstiel S, Suttorp N, Witzenrath M, CAPNETZ and PROGRESS study groups Tags: Am J Respir Crit Care Med Source Type: research