A Combination of the Aerosolized PPAR- γ Agonist Pioglitazone and a Synthetic Surfactant Protein B Peptide Mimic Prevents Hyperoxia-Induced Neonatal Lung Injury in Rats.

CONCLUSIONS: Nebulized PPAR-γ agonist PGZ with a synthetic lung surfactant accelerates lung maturation and prevents neonatal hyperoxia-induced lung injury more than either modality alone, with the potential to provide more effective prevention of BPD. PMID: 29428947 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29428947?dopt=Abstract

Source: Neonatology - February 9, 2018 Category: Perinatology & Neonatology Authors: Sakurai R, Lee C, Shen H, Waring AJ, Walther FJ, Rehan VK Tags: Neonatology Source Type: research

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