Researchers discover another reason for the naked mole rats' long, cancer-free life

(University of Liverpool) A new international study has identified clues concerning the cellular processes that contribute to the naked mole rat's resistance to cancer.
Source: EurekAlert! - Biology - Category: Biology Source Type: news

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In conclusion, CCL20 enhanced doxorubicin resistance of OC cells by regulating ABCB1 expression.Key words: CCL20, ovarian cancer, doxorubicin resistance, tumor-promoting, ABCB1. PMID: 30760665 [PubMed - in process]
Source: Cell Structure and Function - Category: Cytology Authors: Tags: Cell Struct Funct Source Type: research
CONCLUSION: This is the first Asian study to suggest that agriculture/fishery/forestry workers have increased SMRs for NMSC and CM in exposed areas. Early diagnosis of skin cancer in this group is important. PMID: 30761684 [PubMed - as supplied by publisher]
Source: Journal of Occupational Health - Category: Occupational Health Tags: J Occup Health Source Type: research
Glyphosate a chemical in the popular weedkiller Roundup, may elevate cancer risk in people, according to a new study.
Source: Health News - - Category: Consumer Health News Source Type: news
ConclusionThe injuries treated in pets in British Columbia included abscesses, sprains and abrasions. Dogs were also treated with medicinal plants for rheumatoid arthritis, joint pain and articular cartilage injuries. More than 40 plants were used. Anal gland problems were treated with Allium sativum L., Aloe vera L., Calendula officinalis L., Plantago major L., Ulmus fulva Michx., Urtica dioica L. and the lichen Usnea longissima Ach. Antioxidants in plants, such as diarctigenin from Arctium lappa, used in ethnoveterinary medicine for rheumatoid arthritis and joint pain in pets are said to be of use in treating pathologica...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionThe potential pathways and targets that involved in glycolysis to excert the anti-CRC effects of main compounds in triterpenoids of Rhus chinensis Mill. were predicted by network pharmacology methods. Our findings thus provided rational evidence that inhibition of the ASIC2-induced calcineurin/NFAT pathway by triterpenoids in Rhus chinensis Mill. profoundly suppressed cell growth and invasion in CRC, which target alternative glycolysis in colorectal tumor cells, may be a useful adjuvant therapy in the treatment of colorectal cancer.Graphical abstractInhibitory ASIC2-mediated calcineurin/NFAT against colorectal ca...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 14 February 2019Source: International Journal of PharmaceuticsAuthor(s): Gabriela Mojeiko, Moacir de Brito, Giovanna C. Salata, Luciana B. LopesAbstractIn spite of the high incidence of breast cancer worldwide, there are few strategies for its chemoprevention, and they have limited adherence mainly due to their serious adverse effects. As a new approach for local breast cancer chemoprevention, we developed and optimized microemulsions for topical delivery of celecoxib to the breast skin, and evaluated their combination with microneedles to improve drug penetration for localization in the ...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
(CNN) — Glyphosate, an herbicide that remains the world’s most ubiquitous weed killer, raises the cancer risk of those exposed to it by 41%, a new analysis says. Researchers from the University of Washington evaluated existing studies into the chemical — found in weed killers including Monsanto’s popular Roundup — and concluded that it significantly increases the risk of non-Hodgkin lymphoma (NHL), a cancer of the immune system. “All of the meta-analyses conducted to date, including our own, consistently report the same key finding: exposure to GBHs (glyphosate-based herbicides) are asso...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN weed killer Source Type: news
Publication date: Available online 14 February 2019Source: European Journal of Integrative MedicineAuthor(s): Ezgi Karadag EzgiAbstractIntroductionThe aim of this study was to examine the effect of a music listening intervention applied during radiation therapy on the anxiety and comfort level experienced by women with early-stage breast cancer.MethodThis randomized controlled study was conducted with 60 patients residing in a city located in the western Turkey. After providing informed consent, the Hospital Anxiety and Depression Scale (HADS), and Radiation Therapy Comfort Questionnaire (RTCQ) were administered. A music l...
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
ConclusionsUnder treatment conditions, the semiconductor diode does not provide reliable measured data. The probe pushes the rectal wall closer to the high dose areas and underestimates the dose of it. Semiconductor probe is not recommended for in vivo dosimetry of the rectum in image-guided brachytherapy of cervical cancer.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
ConclusionsThe complementary relation between the introduction of IMRT and PTV margin reduction was proven. We found that both approaches need to be implemented to safely deliver a curative dose in dose-escalating prostate radiation therapy.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
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