Cutting out meat may stop breast cancer spreading

Researchers from the Cancer Research UK Cambridge Institute found feeding mice with breast cancer a diet low in the the amino acid  asparagine reduces their tumours' ability to spread.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

Related Links:

Roche today announced the phase III KATHERINE study met its primary endpoint, showing Kadcyla ® (trastuzumab emtansine) as a single agent significantly reduced the risk of disease recurrence or death (invasive disease-free survival, iDFS) compared to Herceptin® (trastuzumab) as an adjuvant (after surgery) treatment in people with HER2-positive early breast cancer (eBC) who have residual di sease (pathological invasive residual disease in the breast and/or axillary nodes) present following neoadjuvant (before surgery) treatment.
Source: Roche Media News - Category: Pharmaceuticals Source Type: news
(Georgetown University Medical Center) A research team, led by investigators from Georgetown Lombardi Comprehensive Cancer Center, details how a natural and dramatic process -- changes in mammary glands to accommodate breastfeeding -- uses a molecular process believed to contribute to survival of pre-malignant breast cells.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
AbstractOptimization of axillary staging among patients converting from clinically node-positive disease to clinically node-negative disease through primary systemic therapy is needed. We aimed at developing a nomogram predicting the probability of positive axillary status after chemotherapy based on clinical/pathological parameters. Patients from study arm C of the SENTINA trial were included. Univariable/multivariable analyses were performed for 13 clinical/pathological parameters to predict a positive pathological axillary status after chemotherapy using logistic regression models. Odds ratios and 95%-confidence-interva...
Source: Clinical and Experimental Metastasis - Category: Cancer & Oncology Source Type: research
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
ConclusionsHigh pre-NAC TIL levels were significantly predictive of pCR in BC, and can act as a surrogate marker for predicting therapeutic effects of a TCHP regimen for HER2-positive BC. Post-NAC TILs in residual disease were a new prognostic marker of risk stratification for long-term survival.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
Journal of Magnetic Resonance Imaging, EarlyView.
Source: Journal of Magnetic Resonance Imaging - Category: Radiology Authors: Source Type: research
Target-based therapeutic matching of phase I trials in patients with metastatic breast cancer in a tertiary referral centre, Published online: 15 October 2018; doi:10.1038/s41416-018-0290-8Target-based therapeutic matching of phase I trials in patients with metastatic breast cancer in a tertiary referral centre
Source: British Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
Profilin-1 deficiency leads to SMAD3 upregulation and impaired 3D outgrowth of breast cancer cells, Published online: 15 October 2018; doi:10.1038/s41416-018-0284-6Profilin-1 deficiency leads to SMAD3 upregulation and impaired 3D outgrowth of breast cancer cells
Source: British Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
ConclusionsThe results of this study indicate that lymphovascular invasion is associated with axillary metastasis, based on an SLN biopsy.
Source: Journal of the Egyptian National Cancer Institute - Category: Cancer & Oncology Source Type: research
Authors: Hwang KT, Han W, Lee SM, Choi J, Kim J, Rhu J, Kim YA, Noh DY Abstract Purpose: The prognostic influence of 3-dimensional tumor volume (Tv) on breast cancer compared to conventional 1-dimensional tumor size (T) was investigated. Methods: Analysis was performed on a cohort of 8,996 primary breast cancer patients who were initially diagnosed with TNM stage I-III. Tumor size was defined as the maximum tumor dimension, and Tv was calculated by the equation of (4π × r1 × r2 × r3)/3; r1, r2, and r3 were defined as half of the largest, intermediate, and shortest dimension of the tumor, re...
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
More News: Breast Cancer | Cancer | Cancer & Oncology | Diets | Health | Meat | Nutrition