Cutting out meat may stop breast cancer spreading
Researchers from the Cancer Research UK Cambridge Institute found feeding mice with breast cancer a diet low in the the amino acid asparagine reduces their tumours' ability to spread.
Authors: D'Andrea F, Ceccarelli M, Facciolà A, Nunnari G, Pellicanò GF, Venanzi Rullo E Abstract With the introduction of HAART, the life expectancy of the patients infected with HIV almost approached that of the general population. The incidence of certain HIV-Associated cancers as Kaposi Sarcoma (KS) and Non-Hodgkin Lymphoma (NHL) decreased, while an increase in Non-AIDS-Defining cancers (NADCs) has been documented. HIV infection is a risk factor for numerous cancers in PLWH. Breast cancer is the most common cancer worldwide among all women. The association between HIV infection and breast cancer ha...
CONCLUSIONS: MiR-34a affects the sensitivity to sunitinib in breast cancer by regulating the Wnt/β-catenin signaling pathway. PMID: 30779084 [PubMed - in process]
Correction: BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors, Published online: 21 February 2019; doi:10.1038/s41436-019-0459-4Correction: BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors
Genome-wide association study of germline variants and breast cancer-specific mortality, Published online: 21 February 2019; doi:10.1038/s41416-019-0393-xGenome-wide association study of germline variants and breast cancer-specific mortality
Sacituzumab, is an antibody that zeroes in on cancer cells. Like a homing missile, it delivers a 'warhead' in the form of a potent chemotherapy drug.
ConclusionsWe found no consistent association between pre-chemotherapy PIM defined by STOPP and outcomes.
In this study, we revisited this claim by independently evaluating the proposed marker haplotype using 2 different patient cohorts recruited in different research settings. Meta-analysis of these new postmastectomy cohorts and the original cohort confirmed significant association of the CACNG2 haplotype with PMP. In addition, we tested whether the same markers would predict chronic postsurgical pain in men who underwent surgery for inguinal hernia repair, and whether there is significant genetic association with cutaneous thermal sensitivity in postmastectomy and postherniotomy patients. We found that the biomarker is sele...
A novel targeted therapy provided an incremental improvement in response rate among breast cancer patients with poor prognoses -- those with heavily pretreated metastatic triple-negative breast cancer (TNBC).Medscape Medical News
WEDNESDAY, Feb. 20, 2019 -- An experimental drug has shown promise in extending the lives of women suffering from a particularly aggressive and deadly type of breast cancer, according to the results of a phase 2 trial. Right now, the standard...