Implementation of a 5-Minute Magnetic Resonance Imaging Screening Protocol for Prostate Cancer in Men With Elevated Prostate-Specific Antigen Before Biopsy
Conclusions A 5-minute MR screening protocol for prostate cancer in men with elevated prostate-specific antigen levels before biopsy is applicable for clinical routine with similar diagnostic performance as the full diagnostic mpMRI approach.
CONCLUSIONS: The combination of TBx and SBx achieved the best results for the detection and prognosis of PCa-s. The use of SBx alone would have missed the detection of PCa-s in 12% of patients. PMID: 29463177 [PubMed - as supplied by publisher]
Conclusion Our results suggest that specific topographic criteria of TZ and AS prostate cancers could add independent information to the usual diagnostic criteria in prostate MRI. Transrectal ultrasound fusion-targeted biopsies based on these specific criteria improve volume estimation of prostate cancers with substantial impact for prognosis and treatment planning.
BackgroundRadiomic analysis is defined as computationally extracting features from radiographic images for quantitatively characterizing disease patterns. There has been recent interest in examining the use of MRI for identifying prostate cancer (PCa) aggressiveness in patients on active surveillance (AS). PurposeTo evaluate the performance of MRI‐based radiomic features in identifying the presence or absence of clinically significant PCa in AS patients. Study TypeRetrospective. Subjects ModelMRI/TRUS (transperineal grid ultrasound) fusion‐guided biopsy was performed for 56 PCa patients on AS who had undergone prebiops...
Indication to pelvic lymph nodes dissection for prostate cancer: the role of multiparametric magnetic resonance imaging when the risk of lymph nodes invasion according to Briganti updated nomogram is
Condition: Prostate Cancer Interventions: Drug: PET/MRI with Gallium-68 labeled PSMA-HBED-CC; Drug: Multiple PET/MRI with Gallium-68 labeled PSMA-HBED-CC; Drug: PET/CT with Gallium-68 labeled PSMA-HBED-CC Sponsor: Weill Medical College of Cornell University Enrolling by invitation
We report late toxicity of a prospective Phase I/II trial employing an MRI assisted focal boost integrated with HDR brachytherapy alone for treatment of low and intermediate risk prostate cancer.
BackgroundPartin tables represent the most widely used predictive tool for prostate cancer stage at prostatectomy but with potential limitations. PurposeTo develop a new PartinMR model for organ‐confined prostate cancer (OCPCA) by incorporating Partin table and mp‐MRI with a support vector machine (SVM) analysis. Study TypeRetrospective. PopulationIn all, 541 patients with biopsy‐confirmed prostate cancer underwent mp‐MRI. Field StrengthT2‐weighted, diffusion‐weighted imaging with a 3.0T MR scanner. AssessmentCandidate predictors included age, prostate‐specific antigen, clinical stage, biopsy Gleason score (G...
ConclusionsThis is the first attempt to model perineural tumor spread and we believe that it provides a glimpse into the future of disease progression monitoring. Every tumor and every patient are different, and the possibility to report treatment response using a unified scale —as “days gained”—will be a necessity in the era of individualized medicine. We hope our work will serve as a springboard for future connections between mathematics and medicine.
Published on 2018-02-07 17:41:45
Conclusions The MRCAT pseudo-CT method provides clinically acceptable accuracy and precision for patient positioning for pelvic radiation therapy based on planar DRR images. Furthermore, due to the reduction of geometric uncertainty, compared to dual-modality workflow, the approach is likely to improve the total geometric accuracy of pelvic radiation therapy. PMID: 29405121 [PubMed - as supplied by publisher]