Implementation of a 5-Minute Magnetic Resonance Imaging Screening Protocol for Prostate Cancer in Men With Elevated Prostate-Specific Antigen Before Biopsy

Conclusions A 5-minute MR screening protocol for prostate cancer in men with elevated prostate-specific antigen levels before biopsy is applicable for clinical routine with similar diagnostic performance as the full diagnostic mpMRI approach.
Source: Investigative Radiology - Category: Radiology Tags: Original Articles Source Type: research

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High dose-rate brachytherapy (HDR-BT) combined with external beam radiotherapy (EBRT) is a widely accepted method of dose escalation in the treatment of localized prostate cancer. The use of magnetic resonance imaging (MRI) to guide needle placement and for planning, enables optimal delineation of the prostate and organs at risk (OAR), potentially improving the treatment ’s therapeutic index. Herein we report early toxicity and health related quality of life (HRQoL) outcomes of a phase II clinical trial of MRI-guided prostate HDR-BT combined with EBRT.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research
Publication date: Available online 22 June 2018 Source:European Urology Author(s): Alberto Briganti, Nicola Fossati, James W.F. Catto, Philip Cornford, Francesco Montorsi, Nicolas Mottet, Manfred Wirth, Hendrik Van Poppel Active surveillance (AS) represents a well-recognized management option for many patients with low- and very low-risk prostate cancer (PCa). AS aims to reduce overtreatment whilst ensuring curative treatment for those in whom it is needed, without losing the window of curability. While long-term series have confirmed the safety of AS in carefully selected patients, this has resulted in new clinical quest...
Source: European Urology - Category: Urology & Nephrology Source Type: research
Objective: a magnetic resonance imaging (MRI)-conditional needle guidance robot is developed to enhance MRI-guided focal laser ablation (FLA) therapy in patients with focal prostate cancer. Methods: inspired by the workflow of the manual FLA therapy, we developed an MRI-conditional robot with two degrees of freedom to provide the guidance for laser ablation catheter. This robot is powered by pneumatic turbine motors and encoded with the custom-designed optical encoder. The needle could be inserted manually through the designed robotic system, which keeps the patients inside MRI bore throughout the procedure. The robot hard...
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Asia-Pacific Journal of Clinical Oncology, EarlyView.
Source: Asia-Pacific Journal of Clinical Oncology - Category: Cancer & Oncology Authors: Source Type: research
Conclusions It has been shown that the test performance of PI-RADS v2 in research and clinical practice is improved, retaining higher accuracy over systematic TRUS biopsies for PCa diagnosis. Patient summary Multiparametric magnetic resonance imaging (MRI) and MRI-directed biopsies using the Prostate Imaging-Reporting and Data System improves the detection of prostate cancers likely to cause harm, and at the same time decreases the detection of disease that does not lead to harms if left untreated. The keys to success are high-quality imaging, reporting, and biopsies by radiologists and urologists working together in multi...
Source: European Urology - Category: Urology & Nephrology Source Type: research
Prostate cancer is the second most common cancer in men worldwide [1], and is the fifth leading cause of cancer death in men with 307,500 deaths in 2012 [1]. Approximately two-thirds of prostate cancer cases are disproportionately diagnosed in the developed world, largely due to prostate cancer screening practices [1]. However, some detected cancers are so low grade and slow growing that they are unlikely to affect the individual in his lifetime [2]. Treatment with radical prostatectomy, brachytherapy, or external bean radiotherapy carries risks including erectile dysfunction and urinary incontinence [2].
Source: Canadian Association of Radiologists Journal - Category: Radiology Authors: Tags: Abdominal Imaging / Imagerie abdominale Source Type: research
AbstractIntroductionLong-term outcomes from large cohorts are not yet available upon which to base recommended follow-up protocols after prostate focal therapy. This is an updated summary of a 2015 SIU-ICUD review of the best available current evidence and expert consensus on guidelines for surveillance after prostate focal therapy.MethodsWe performed a systematic search of the PubMed, Cochrane and Embase databases to identify studies where primary prostate focal therapy was performed to treat prostate cancer.ResultsMultiparametric magnetic resonance imaging (mpMRI) should be performed at 3 –6 months, 12–2...
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
BJU International, EarlyView.
Source: BJU International - Category: Urology & Nephrology Authors: Source Type: research
BJU International, EarlyView.
Source: BJU International - Category: Urology & Nephrology Authors: Source Type: research
The Michigan Urological Surgery Improvement Collaborative (MUSIC) program has transformed both population management and quality improvement in urology. In the current study,1 the authors address an important and timely question: do men on active surveillance pursue confirmatory testing after diagnosis of favorable-risk prostate cancer and, when they do, do they persist on active surveillance? In addition to delineating current practices in Michigan of confirmatory testing —the most common being the use of molecular classifiers (55%), followed by magnetic resonance imaging (MRI, 34%) and repeat biopsy (11%), the stud...
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
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