Wyss Center announces collaboration with CorTec
(Wyss Center for Bio and Neuroengineering) The Wyss Center, a non-profit neurotechnology translation organization, has signed a partnership agreement with German medical engineering company, CorTec. The partners will work together on research, design and development of a device for continuous, long-term, monitoring of the brain's electrophysiological signals for clinical diagnostic and therapeutic applications. The planned device will sit on the skull, beneath the skin and has potential uses in epilepsy monitoring, tinnitus regulation through neurofeedback, neuromodulation for dyslexia and other brain circuit disorders.
Publication date: Available online 18 October 2018Source: Epilepsy &Behavior Case ReportsAuthor(s): Jason Lockrow, Hannah Tully, Russell SanetoAbstractCongenital TORCH infections are a significant cause of epileptic spasms, an infantile epileptic encephalopathy, through disruptions to several pathways in neurodevelopment. Congenital Zika virus has a similar neurotropism to other TORCH agents, and leads to microcephaly, severe neurodevelopmental impairment, and high rates of early onset seizures. Here we report a child with confirmed congenital Zika virus who developed extensor epileptic spasms and hypsarrhythmia associ...
We report on a girl affected by epileptic seizures treated with levetiracetam for five years. Due to worsening of the seizures, the dosage of this drug was increased and afterwards lowdosage topiramate was initiated. After 12 days from the introduction of topiramate, the girl began to present neurologic signs including limbs rigidity, pain, incoordination and flexed fingers. Gradual withdrawn of the topiramate resulted in progressive resolution of the symptomatology. This clinical episode could represent a probable topiramate-related side effect (Naranjo score 5), never reported before in this form. PMID: 29437013 [Pu...
Conclusion: It is worth mentioning that the proposed study utilized a single linear feature to predict seizures precisely. Moreover, utilization of single feature encouraged in subsiding system complexity, processing delays, and system latency. PMID: 30332347 [PubMed - as supplied by publisher]
A new genetic cause of severe, difficult-to-treat childhood epilepsy syndrome has been identified, offering clues to potential medical treatments.
CONCLUSION: Dural arteriovenous fistula is an uncommon intracranial vascular malformation rarely seen by otolaryngologists, with pulsatile tinnitus being the usual presentation. To our knowledge, this is the first reported case of dural arteriovenous fistula presenting with conductive hearing loss and otalgia. PMID: 30322412 [PubMed - as supplied by publisher]
Conditions: Tinnitus; Noise Induced Tinnitus; Tinnitus, Subjective; Tinnitus, Objective; Tinnitus Aggravated; Tinnitus, Pulsatile; Tinnitus, Spontaneous Oto-Acoustic Emission; Tinnitus, Clicking; Tinnitus, Tensor Tympani Induced Intervention: Behavioral: Meditation Sponsors: State University of New York at Buffalo; University at Buffalo Recruiting
ABSTRACT Sleepiness and cognitive impairment are common symptoms observed in patients with epilepsy. We investigate whether self-reported sleepiness is associated with cognitive performance in patients with refractory mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). Seventy-one consecutive patients with MTLE-HS were evaluated with the Stanford Sleepiness Scale (SSS) before neuropsychological evaluation. Their mean SSS scores were compared with controls. Each cognitive test was compared between patients with (SSS ≥ 3) or without sleepiness (SSS
Publication date: November 2018Source: Epilepsy &Behavior, Volume 88Author(s): Aline Priscila Pansani, Roberta Monterazzo Cysneiros, Diego Basile Colugnati, Luciana Janjoppi, Danuza Ferrari, Eliângela de Lima, Poliana Peres Ghazale, Rita Sinigaglia-Coimbra, Fulvio Alexandre ScorzaAbstractThe imbalance between antioxidant system and reactive oxygen species (ROS) generation is related to epileptogenesis, neuronal death, and seizure frequency. Treatment with vitamin E has been associated with neuroprotection and control of seizures. In most experimental studies, vitamin E treatment has short duration. Therefore, the...
ConclusionIn the majority of cases, epilepsy relapse occurred within the first two years after the initiation of AED withdrawal. The independent risk factors of seizure relapse were uncontrolled seizures beyond the first 6 months of AED therapy and cases with a history of perinatal injury.