Wyss Center announces collaboration with CorTec

(Wyss Center for Bio and Neuroengineering) The Wyss Center, a non-profit neurotechnology translation organization, has signed a partnership agreement with German medical engineering company, CorTec. The partners will work together on research, design and development of a device for continuous, long-term, monitoring of the brain's electrophysiological signals for clinical diagnostic and therapeutic applications. The planned device will sit on the skull, beneath the skin and has potential uses in epilepsy monitoring, tinnitus regulation through neurofeedback, neuromodulation for dyslexia and other brain circuit disorders.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Publication date: Available online 16 April 2019Source: Best Practice &Research Clinical Endocrinology &MetabolismAuthor(s): German Rubinstein, Andrea Osswald, Stephanie Zopp, Katrin Ritzel, Marily Theodoropoulou, Felix Beuschlein, Martin ReinckeAbstractCONTEXT:Cushing’s disease (CD) is the most common etiology of Cushing’s syndrome (CD) due to corticotroph pituitary adenoma, which are in most cases small (80-90% microadenomas) and in about 40% cannot be visualized on imaging of the sella. First-line treatment for CD is transsphenoidal surgery (TSS) with the aim of complete adenoma removal and preservat...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Hongye Zhao1,2, Tiezheng Zheng1, Xiaohan Yang1, Ming Fan3, Lingling Zhu3, Shuhong Liu3, Liying Wu3 and Changkai Sun1,4* 1Department of Physiology and Key Laboratory of Brain Diseases of Liaoning Province, School of Basic Medical Sciences, Dalian Medical University, Dalian, China 2Department of Physiology, School of Basic Medical Sciences, Qiqihar Medical University, Qiqihar, China 3Department of Brain Protection and Plasticity, Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing, China 4Department of Biomedical Engineering, Faculty of Electronic Information and Electrical Engineerin...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Grand Total EEG Score Can Differentiate Parkinson's Disease From Parkinson-Related Disorders Ela Austria Barcelon1,2*, Takahiko Mukaino1, Jun Yokoyama1, Taira Uehara2, Katsuya Ogata2, Jun-ichi Kira1 and Shozo Tobimatsu2 1Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan2Department of Clinical Neurophysiology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Background: Semi-quantitative electroencephalogram (EEG) analysis is easy to perform and has been used to differentiate dementias, as well ...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Conclusion The m.10191T>C mutation in the mtDNA of the complex I (CI) subunit of MTND3 results in the substitution of a highly conserved amino acid (p.Ser45Pro) within the ND3 protein, leading to CI dysfunction through impaired enzyme catalysis rather than impaired stability or assembly, causing a broad clinical spectrum of disorders (26). Patients with the m.10191T>C mutation are rare. In the present study, we report on a family of patients with the extremely rare adult-onset Leigh-like syndrome with the m.10191T>C mutation. Including the two patients from our reported family, the m.10191T>C mutation has bee...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
In this study, the StCas9 derived from Streptococcus thermophilus together with the Drosha-mediated sgRNA-shRNA structure were combined to boost the G to A base editing on the IGF2 SNP site, which we called “SNP editing.” The codon-humanized StCas9 as we previously reported was firstly compared with the prevalently used SpCas9 derived from Streptococcus pyogenes using our idiomatic surrogate report assay, and the StCas9 demonstrated a comparable targeting activity. On the other hand, by combining shRNA with sgRNA, simultaneous gene silencing and genome targeting can be achieved. Thus, the novel IGF2.sgRNA-LIG4....
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Conclusion: This case of thyroid bed PG supports the idea that PG reflects a cutaneous phenotype encompassed in the spectrum of systemic neutrophilic diseases. Endocrinologists should be aware that thyroid bed PG involvement is an albeit rare differential diagnosis to consider in patients who had undergone thyroid surgery, especially with a history of PG. Introduction Papillary thyroid carcinoma (PTC), the main variant of differentiated thyroid carcinoma (DTC), is the most common thyroid cancer, accounting for 70–80% of all thyroid carcinomas and occurring predominantly in women, generally with a good prognos...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Tatsuya Daikoku1,2* and Masato Yumoto1 1Department of Clinical Laboratory, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan 2Department of Neuropsychology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany In an auditory environment, humans are frequently exposed to overlapping sound sequences such as those made by human voices and musical instruments, and we can acquire information embedded in these sequences via attentional and nonattentional accesses. Whether the knowledge acquired by attentional accesses interacts with that acquired by nonattentional accesses is...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
Therapeutic Targeting of Fibrotic Epithelial-Mesenchymal Transition–An Outstanding Challenge Attila Fintha1, Ákos Gasparics2, László Rosivall3 and Attila Sebe3,4* 12nd Department of Pathology, Semmelweis University, Budapest, Hungary 21st Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary 3Department of Pathophysiology, International Nephrology Research and Training Center, Semmelweis University, Budapest, Hungary 4Division of Medical Biotechnology, Paul Ehrlich Institute, Langen, Germany Back in 1995, a landmark paper was published, which shaped the fi...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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Source: Journal of Physical Activity and Health - Category: Sports Medicine Tags: J Phys Act Health Source Type: research
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Source: Quality of Life Research - Category: Health Management Source Type: research
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